Research

Macro partitioning

A higher dietary fat-to-carbohydrate ratio in African-American children correlates negatively with insulin sensitivity and insulin clearance, and positively with fasting free fatty acids and first-phase insulin secretion.

For families concerned about metabolic health, the balance of macronutrients matters. This study found that a higher ratio of fat to carbohydrates in the diet was associated with lower insulin sensitivity and clearance in children. While this does not prescribe a specific diet, it suggests that monitoring the quality and ratio of fats and carbohydrates may be relevant for metabolic health, especially in African-American children who may have lower baseline insulin clearance.

ModerateSupportsMEDIUM confidence
Both insulin clearance and insulin sensitivity correlated inversely with dietary fat/carbohydrate ratio, which was higher in AA than in white children.
Silva Arslanian et al. · Diabetes · 2002

Why this rating

Based on 24-hour food recalls (self-reported) and cross-sectional correlation, not a randomized dietary intervention.

Source

Hyperinsulinemia in African-American Children

Silva Arslanian et al. · Diabetes · 2002

DOI 10.2337/diabetes.51.10.3014

cross_sectional · n=44Cited 237×
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DOI resolved against Crossref · corpus check 2026-06-10

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