Research

Hormonal

GLP-1 receptor agonists reduce food intake and body weight in humans, with efficacy comparable to or rivaling bariatric surgery.

GLP-1 medications are effective for weight loss and may eventually rival bariatric surgery in efficacy. They offer a non-surgical option for treating obesity.

StrongSupportsHIGH confidence
Progressive improvements in the efficacy of GLP1RA suggest that GLP-1-based therapies may soon rival bariatric surgery as viable options for the treatment of obesity and its complications.
Daniel J. Drucker · Molecular Metabolism · 2021

Why this rating

Based on multiple clinical trials and a comprehensive review.

Source

GLP-1 physiology informs the pharmacotherapy of obesity

Daniel J. Drucker · Molecular Metabolism · 2021

narrative_reviewCited 454×
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