Hormonal
Chronic hyperglycemia, indicated by elevated HbA1c levels, is associated with persistently lower muscle strength and muscle quality in aging adults, independent of muscle mass loss.
If you have elevated blood sugar levels (even if not yet diagnosed as diabetes), prioritize glycemic control not just for organ health, but to preserve muscle strength. This study suggests that high blood sugar directly harms muscle function, independent of how much muscle you have. Focus on managing blood glucose through diet and lifestyle to maintain mobility and reduce disability risk as you age.
Hyperglycemia is associated with persistently lower muscle strength with aging, but this effect may be mediated, at least in part, by peripheral neuropathy.
Why this rating
Longitudinal observational study with large sample size (n=984) and long follow-up, but observational design limits causal inference.
Source
Hyperglycemia Predicts Persistently Lower Muscle Strength With Aging
Rita R. Kalyani et al. · Diabetes Care · 2014
DOI 10.2337/dc14-1166
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