Research
Macro partitioning
A hypocaloric hyperproteic diet (800 kcal deficit, 35% protein) improves insulin sensitivity and reduces androgen levels in obese PCOS patients, leading to improved menstrual cyclicity.
A diet with a moderate caloric deficit (800 kcal) and high protein (35%) improves metabolic markers in obese PCOS patients. However, adherence is challenging, with higher dropout rates compared to exercise programs.
ModerateSupportsMEDIUM confidence
Body weight, body mass index, waist circumference, insulin resistance indexes and serum levels of sex hormone-binding globulin, androstenedione and dehydroepiandrosterone sulphate changed significantly (P < 0.05) from baseline and were significantly different (P < 0.05) between the two groups.
Why this rating
Same limitations as N1 (pilot, small n, non-randomized).
Source
Structured exercise training programme versus hypocaloric hyperproteic diet in obese polycystic ovary syndrome patients with anovulatory infertility: a 24-week pilot study
Stefano Palomba et al. · Human Reproduction · 2007
DOI 10.1093/humrep/dem391
cohort · n=40Cited 236×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
Related findings · Macro partitioning
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