Hormonal
Sleep deprivation and reduced sleep duration weaken the immune response, increasing susceptibility to viral, bacterial, and parasitic infections through mechanisms such as impaired lymphocyte proliferation and altered cytokine levels.
Prioritize adequate sleep duration and quality as a primary defense against infection. Sleep deprivation directly impairs immune cell function (lymphocytes, NK cells) and cytokine signaling, making you more susceptible to colds and other infections. Treat sleep with the same importance as nutrition and training.
a lack of sleep can weaken immunity, increasing organism susceptibility to infection. For instance, shorter sleep durations are associated with a rise in suffering from the common cold.
Why this rating
The paper is a review citing multiple human and animal studies, providing strong mechanistic evidence, though it lacks a single definitive clinical trial on sleep duration and infection rates in healthy adults.
Source
The Bidirectional Relationship between Sleep and Immunity against Infections
Elizabeth Ibarra‐Coronado et al. · Journal of Immunology Research · 2015
DOI 10.1155/2015/678164
More from this paper
- Specific cytokines (IL-1, TNF, IFN) produced during the immune response act on the brain to increase non-REM sleep duration, demonstrating a bidirectional communication between the immune system and sleep regulation.Strong
- Infection and immune response actively alter sleep patterns, typically increasing slow-wave sleep (SWS) and decreasing REM sleep, which may be an adaptive mechanism to conserve energy for the immune response.Good
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