Hormonal

In insulin-resistant subjects, a carbohydrate-rich diet redistributes body fat to central depots and decreases postprandial peripheral adiponectin gene expression, whereas a monounsaturated fat (MUFA)-rich diet prevents this central fat redistribution and maintains higher adiponectin expression.

If you are insulin resistant, eating a high-carbohydrate diet may cause your body to store fat in your belly (central depot) and reduce protective adiponectin levels, even if you don't gain overall weight. Switching to a diet rich in monounsaturated fats (like olive oil) can help prevent this central fat accumulation and maintain better insulin sensitivity compared to high-carb or high-saturated-fat diets, provided total calories remain stable.