Hormonal
High-intensity interval training (HIIT) induces skeletal muscle molecular adaptations, including increased GLUT-4 content and mitochondrial biogenesis, which improve glucose disposal and insulin sensitivity in patients with metabolic diseases.
If you have metabolic issues like type 2 diabetes, high-intensity interval training (HIIT) can significantly improve how your muscles handle glucose. This involves short bursts of vigorous activity followed by rest, which increases GLUT-4 proteins and mitochondrial function. Consult your doctor to ensure it is safe for you, then consider protocols that challenge your peak heart rate (80-95% HRmax) for intervals of 1-4 minutes.
Skeletal muscle is the primary site for glucose disposal via insulin- and non-insulin-mediated glucose uptake... Increased GLUT-4 content in the vastus lateralis increased by 369% following six sessions of HIIT in type 2 diabetes patients [12].
Why this rating
The paper is a review summarizing various studies; specific effect sizes vary, and some findings are from small sample sizes.
Source
High-intensity interval training: a review of its impact on glucose control and cardiometabolic health
Sophie Cassidy et al. · Diabetologia · 2016
DOI 10.1007/s00125-016-4106-1
More from this paper
- A single session of HIIT reduces same-day postprandial glucose excursions in individuals with impaired fasting glucose or type 2 diabetes, offering acute metabolic benefits.Moderate
- HIIT improves cardiovascular function in patients with metabolic diseases by increasing end-diastolic volume, stroke volume, and flow-mediated dilation, and reducing arterial stiffness.Moderate
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