Hormonal
Dietary supplementation with inulin-type fructans (prebiotics) reduces body weight gain and fat mass development in obese subjects by modulating gut peptides (increasing GLP-1, PYY, and decreasing ghrelin) and improving gut barrier integrity.
To manage weight and fat mass, incorporate inulin-type fructans (found in foods like chicory root, garlic, onions, or as supplements) into your daily diet. Studies suggest doses between 8g and 21g per day can help reduce body weight gain and fat mass in obese individuals and maintain BMI in adolescents. This works by increasing satiety hormones (GLP-1, PYY) and reducing hunger hormones (ghrelin), while also improving gut health.
Ingestion of inulin-type fructans prebiotic (8g/d) for one year showed a significant benefit in the maintenance of BMI, and fat mass in non obese young adolescents... The daily intake of yacon syrup... increased satiety sensation and decreased body weight, waist circumference and body mass index in obese pre-menopausal women... short chain inulin-type fructan were given as a supplement for 3 months (21g/d), decreased food intake, body weight gain and fat mass development in obese subjects
Why this rating
The paper cites multiple human intervention studies but notes they are limited in number and duration compared to animal models.
Source
Modulation of the gut microbiota by nutrients with prebiotic properties: consequences for host health in the context of obesity and metabolic syndrome
Nathalie M. Delzenne et al. · Microbial Cell Factories · 2011
DOI 10.1186/1475-2859-10-s1-s10
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