Hormonal
Astragalus improves intestinal barrier function and immunity by modulating intestinal microbiota, thereby treating Type 2 Diabetes Mellitus (T2DM).
For individuals with T2DM, incorporating Astragalus (specifically its polysaccharides, saponins, and flavonoids) may support gut health and insulin sensitivity. The herb works by improving the intestinal barrier and modulating gut bacteria to reduce inflammation and improve glucose metabolism. Consult a healthcare provider before use, especially if taking other diabetes medications.
Astragalus improves intestinal barrier function and immunity by acting on intestinal microbiota to treat T2DM: a research review
Why this rating
The paper is a review of animal and in vitro studies; no human clinical trials are detailed in the text.
Source
Astragalus improves intestinal barrier function and immunity by acting on intestinal microbiota to treat T2DM: a research review
Su Min et al. · Frontiers in Immunology · 2023
DOI 10.3389/fimmu.2023.1243834
More from this paper
- Astragalus polysaccharides (APS) improve T2DM outcomes by increasing the abundance of beneficial bacteria (e.g., Bifidobacterium, Lactobacillus) and short-chain fatty acids (SCFAs), while reducing insulin resistance.Moderate
- Astragaloside IV (AS-IV), a saponin in Astragalus, reduces blood glucose and insulin resistance by modulating intestinal microbiota to increase butyric acid and activating PI3K/AKT and AMPK/SIRT1 signaling pathways.Moderate
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