Hormonal
Interindividual variability in triglyceride response to low-fat, high-carb diets is determined by the 24-hour pattern of fatty acid synthesis (constant vs. diurnal), not by body mass index or insulin levels.
Not everyone reacts to low-fat, high-carb diets with high triglycerides. Your response depends on whether your body maintains high fat synthesis constantly throughout the day or only spikes after meals. Those with 'constant' high synthesis have much higher triglycerides, regardless of their weight or insulin levels.
Thus, on the 10% fat diet, the 'constant' pattern of fatty acid synthesis was associated with much higher TG levels than the 'diurnal' pattern.
Why this rating
Robust data showing distinct patterns and their correlation with TG levels.
Source
Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects
Lisa C. Hudgins et al. · Journal of Lipid Research · 2000
DOI 10.1016/s0022-2275(20)32407-x
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