Research
Hormonal
Gastric bypass (RYGBP) leads to enhanced postprandial suppression of ghrelin and increased PYY secretion compared to gastric banding and controls, which may contribute to reduced food intake.
Roux-en-Y gastric bypass increases the secretion of PYY and enhances the suppression of ghrelin after eating. These hormonal changes are associated with reduced food intake and may help patients feel fuller sooner and eat less compared to those who undergo gastric banding or no surgery.
GoodSupportsHIGH confidence
Patients who had undergone RYGBP had increased postprandial PYY secretion and enhanced suppression of ghrelin, and this may contribute to reduce food intake.
Why this rating
Same study limitations as N1, but the hormonal data is robustly measured.
Source
Effects of Gastric Bypass and Gastric Banding on Glucose Kinetics and Gut Hormone Release
Frédérique Rodieux et al. · Obesity · 2008
DOI 10.1038/oby.2007.83
cross_sectional · n=22Cited 214×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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