Hormonal
Activation of beige adipose tissue (browning of white fat) improves glucose homeostasis and insulin sensitivity, offering a therapeutic mechanism for type 2 diabetes.
You can potentially improve your metabolic health by encouraging your body to create 'beige fat' within your white fat stores. This happens naturally through exposure to cold temperatures and regular exercise. While you cannot directly 'eat' beige fat, these lifestyle factors trigger the browning process, which helps clear glucose and lipids from your blood, thereby improving insulin sensitivity.
Brown and beige adipose tissues have been demonstrated to play a role in glucose homeostasis, insulin sensitivity, and lipid metabolism—all factors related to pathogenesis of type 2 diabetes.
Why this rating
The paper is a review summarizing multiple animal models and some human studies; it establishes strong mechanistic plausibility but lacks a single definitive large-scale human clinical trial.
Source
Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes
Anna Kaisanlahti et al. · Journal of Physiology and Biochemistry · 2018
DOI 10.1007/s13105-018-0658-5
More from this paper
- Cold exposure and beta-3 adrenergic agonists are primary physiological and pharmacological agents that induce the browning of white adipose tissue.Good
- Dietary compounds such as capsaicin, resveratrol, berberine, and green tea extract can induce browning of white adipose tissue in animal models.Moderate
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