Research
Macro partitioning
Intermittent feeding or short periods of fasting can partially reverse biochemical EFA deficiency by mobilizing linoleic acid from adipose tissue stores.
If you are on a fat-free diet, incorporating short periods of fasting or switching to intermittent feeding can help your body access stored essential fatty acids, potentially mitigating deficiency symptoms.
GoodSupportsHIGH confidence
With increased free fatty acid outflow during fasting and intermittent feeding, linoleic acid rose and eicosatrienoic acid decreased.
Why this rating
Supported by detailed metabolic tracking in Study II.
Source
The development of essential fatty acid deficiency in healthy men fed fat-free diets intravenously and orally.
Jamie Dollahite Wene et al. · Journal of Clinical Investigation · 1975
DOI 10.1172/jci108061
crossover · n=9Cited 213×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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