Hormonal
Following a single bout of resistance exercise, activated satellite cells (MyoD+) are located significantly closer to capillaries than quiescent satellite cells (MyoD-) in young men, suggesting that proximity to capillaries facilitates SC activation.
Resistance exercise triggers satellite cells to activate, and these activated cells tend to be closer to blood vessels, which likely helps deliver the nutrients and signals they need to repair muscle. This highlights the importance of resistance training for maintaining muscle health, especially as we age.
In addition, activated vs. quiescent SC were situated closer (P < 0.05) to capillaries.
Why this rating
Clear statistical difference (P < 0.05) observed in a subset of young men after a standardized exercise protocol.
Source
Skeletal muscle satellite cells are located at a closer proximity to capillaries in healthy young compared with older men
Joshua P. Nederveen et al. · Journal of Cachexia Sarcopenia and Muscle · 2016
DOI 10.1002/jcsm.12105
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