Hormonal
High dietary glycemic index and glycemic load are associated with significantly lower plasma adiponectin levels in men with type 2 diabetes, whereas high cereal fiber intake is associated with higher levels.
If you have type 2 diabetes, focus on reducing your overall glycemic load and glycemic index by choosing whole, unrefined carbohydrate sources rich in cereal fiber (like whole grains) rather than refined carbs. This dietary pattern is associated with higher levels of adiponectin, a hormone that improves insulin sensitivity and reduces inflammation.
After adjustment for age, BMI, smoking, alcohol consumption, physical activity, aspirin use, HbA1c, history of hypertension or hypercholesterolemia, and fiber intake, dietary glycemic index and glycemic load were inversely associated with plasma adiponectin in a dose-dependent fashion... In contrast, high intake of cereal fiber was associated with increased plasma adiponectin levels
Why this rating
Observational cross-sectional design limits causal inference, despite rigorous adjustment for confounders.
Source
Dietary Glycemic Index, Glycemic Load, Cereal Fiber, and Plasma Adiponectin Concentration in Diabetic Men
Lu Qi et al. · Diabetes Care · 2005
DOI 10.2337/diacare.28.5.1022
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