Research
Macro partitioning
Substituting saturated fats and trans fats with unsaturated fats (MUFA and PUFA) reduces total mortality, whereas substituting carbohydrates with saturated or trans fats increases mortality.
Focus on the quality of your macronutrients. Replace saturated and trans fats with unsaturated fats (nuts, olive oil, fish). Avoid replacing carbohydrates with animal fats; instead, choose unsaturated fats or plant-based proteins if reducing carbs.
GoodSupportsMEDIUM confidence
When SFA and trans fatty acids were substituted for total carbohydrate, a higher risk of mortality ensued, but when PUFA and MUFA were substituted for carbohydrate... a significant reduction in mortality was observed.
Why this rating
Based on large prospective cohorts (NHS/HPFS) with substitution analysis, though observational design limits causal inference compared to RCTs.
Source
Dietary Fats and Chronic Noncommunicable Diseases
Hayley Billingsley et al. · Nutrients · 2018
narrative_reviewCited 109×
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