Research

Macro partitioning

Ad libitum low-fat diets varying in protein content and glycemic index are feasible for long-term weight maintenance in obese families, with high protein and low glycemic index diets designed to regulate appetite and prevent weight regain.

To maintain weight loss, consider shifting focus from strict calorie counting to macronutrient quality. The Diogenes study design suggests that ad libitum consumption of low-fat diets with higher protein and lower glycemic index may help regulate appetite and prevent weight regain, especially when supported by structured dietary counseling and accessible healthy food options.

ModerateSupportsMEDIUM confidence
The five diets were all designed as low-fat (25–30 E%) ad libitum diets (i.e. no energy restrictions on total energy intake) so as to test the diets’ ability to regulate appetite and body weight.
Thomas Meinert Larsen et al. · Obesity Reviews · 2009

Why this rating

This is a study protocol/design paper; it establishes feasibility and baseline characteristics but does not report efficacy results.

Source

The Diet, Obesity and Genes (Diogenes) Dietary Study in eight European countries – a comprehensive design for long‐term intervention

Thomas Meinert Larsen et al. · Obesity Reviews · 2009

DOI 10.1111/j.1467-789x.2009.00603.x

rct · n=891Cited 203×
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DOI resolved against Crossref · corpus check 2026-06-10

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