Research

Adherence

Supervised moderate-to-high intensity aerobic training (60-100% VO2peak) performed three times weekly during neoadjuvant chemotherapy for breast cancer is safe and significantly improves cardiopulmonary function (VO2peak) compared to chemotherapy alone.

If you are undergoing breast cancer chemotherapy, supervised aerobic exercise (cycling) 3 times a week at moderate-to-high intensity is safe and can significantly improve your heart and lung capacity, which typically declines during treatment. Start with supervision to ensure safety and proper intensity progression.

ModerateSupportsMEDIUM confidence
Moderate-to-high intensity aerobic training when conducted with one-on-one supervision is a safe adjunct therapy associated with improvements in cardiopulmonary function and select PROs during neoadjuvant chemotherapy.
Whitney Hornsby et al. · Acta Oncologica · 2013

Why this rating

Phase II randomized trial with small sample size (n=20) and short duration (12 weeks).

Source

Safety and efficacy of aerobic training in operable breast cancer patients receiving neoadjuvant chemotherapy: A phase II randomized trial

Whitney Hornsby et al. · Acta Oncologica · 2013

DOI 10.3109/0284186x.2013.781673

rct · n=20Cited 196×
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DOI resolved against Crossref · corpus check 2026-06-10

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