Macro partitioning
In middle-aged men without prior cardiovascular disease or diabetes, total intake and specific types of dietary fat (saturated, monounsaturated, polyunsaturated, trans) and dietary cholesterol are not associated with the risk of ischaemic or haemorrhagic stroke.
For men without existing heart disease or diabetes, current evidence from this large study suggests that you do not need to strictly restrict total fat, saturated fat, or cholesterol intake specifically to prevent stroke. Focus on a balanced diet rather than fearing specific fat types for stroke prevention.
After adjustment for age, smoking, and other potential confounders, no evidence was found that the amount or type of dietary fat affects the risk of developing ischaemic or haemorrhagic stroke.
Why this rating
Large prospective cohort (n=43,732), long follow-up (14 years), rigorous adjustment for confounders, but observational design limits causal inference.
Source
Dietary fat intake and risk of stroke in male US healthcare professionals: 14 year prospective cohort study
Ka He et al. · BMJ · 2003
DOI 10.1136/bmj.327.7418.777
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