Hormonal
Vitamin D deficiency (serum 25(OH)D < 25 nmol/L) is an independent predictor of increased mortality in patients with heart failure, while vitamin D supplementation is associated with reduced mortality in this population.
If you have heart failure, ask your doctor to check your Vitamin D levels. This study suggests that deficiency is linked to higher mortality risk, and supplementation (typically 800-1000 IU/day in this study) was associated with better survival outcomes. Ensure your levels are optimized as part of your overall heart health management.
Cox regression analysis demonstrated that vitamin D deficiency was an independent predictor of increased mortality in patients with HF [hazard ratio (HR) 1.52, 95% confidence interval (CI) 1.21 –1.92, P < 0.001]... Vitamin D supplementation was independently associated with reduced mortality in HF patients (HR 0.68, 95% CI 0.54–0.85, P < 0.0001).
Why this rating
Observational cohort study with large sample size (n=3009 HF patients) and adjustment for confounders, but not a randomized controlled trial proving causality for supplementation.
Source
Vitamin D Deficiency is a Predictor of Reduced Survival in Patients with Heart Failure; Vitamin D Supplementation Improves Outcome
Israel Gotsman et al. · European Journal of Heart Failure · 2012
DOI 10.1093/eurjhf/hfr175
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