Research

Macro partitioning

Mediterranean Diet (MD) interventions significantly improve liver enzymes (ALT, AST), Fatty Liver Index, and liver stiffness in NAFLD patients, often with higher adherence than other diets.

Adopting a Mediterranean-style dietary pattern is an effective strategy for improving liver health in NAFLD. This involves increasing fiber, fruits, nuts, and healthy fats (like olive oil) while reducing refined carbohydrates and sodium. This approach not only improves liver enzymes and fat content but also tends to have higher patient adherence compared to other restrictive diets.

GoodSupportsHIGH confidence
MD reduced ALT (P = 0.02), FLI (P < 0.001) and liver stiffness (P = 0.05)... MD adherence was higher in MD groups [35,39,42] with increased consumption of fibre [35], fruit [42] and nuts [28].
Laura Haigh et al. · Clinical Nutrition · 2022

Why this rating

Meta-analysis of 13 MD studies, though heterogeneity in intervention components exists.

Source

The effectiveness and acceptability of Mediterranean diet and calorie restriction in non-alcoholic fatty liver disease (NAFLD): A systematic review and meta-analysis

Laura Haigh et al. · Clinical Nutrition · 2022

Meta-analysis · 26 studiesCited 193×
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