Hormonal
The risk reduction of new-onset atrial fibrillation following bariatric surgery is significantly greater in younger individuals and those with higher baseline diastolic blood pressure.
Younger patients with severe obesity and high blood pressure are likely to derive the greatest protective benefit against atrial fibrillation from bariatric surgery. The protective effect diminishes in older patients and those with lower baseline blood pressure, though the overall risk reduction remains significant.
Younger individuals benefited more from surgical intervention than those who were older (p value for interaction 0.001). Also, those with a high diastolic blood pressure benefitted more from surgery than did those with a low diastolic blood pressure (p for interaction = 0.028).
Why this rating
Based on the same high-quality SOS cohort data with statistical interaction tests.
Source
Bariatric Surgery and the Risk of New-Onset Atrial Fibrillation in Swedish Obese Subjects
Shabbar Jamaly et al. · Journal of the American College of Cardiology · 2016
DOI 10.1016/j.jacc.2016.09.940
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