Research

Hormonal

Women with Premenstrual Dysphoric Disorder (PMDD) exhibit more severe sleep disturbances and altered circadian hormone rhythms (specifically melatonin and cortisol) during the luteal phase compared to healthy women, including phase delays in melatonin and reduced melatonin amplitude.

If you have PMDD, your sleep issues are likely tied to a physiological resistance to melatonin and altered hormone rhythms during the week before your period. This is a recognized medical condition, not just 'stress'. Discussing chronotherapeutic treatments or hormone-regulating strategies with a healthcare provider may be more effective than standard sleep hygiene advice alone.

ModerateQualifiesMEDIUM confidence
These complaints reach a higher severity in women suffering from premenstrual dysphoric disorder (PMDD)... In PMDD: ↓ AUC, ↓ amplitude, ↓ duration, delayed onset during late-LP
Ari Shechter et al. · International Journal of Endocrinology · 2010

Why this rating

The paper notes inconsistencies in the literature regarding hormone rhythms, but highlights specific, severe findings in PMDD patients compared to controls.

Source

Sleep, Hormones, and Circadian Rhythms throughout the Menstrual Cycle in Healthy Women and Women with Premenstrual Dysphoric Disorder

Ari Shechter et al. · International Journal of Endocrinology · 2010

DOI 10.1155/2010/259345

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DOI resolved against Crossref · corpus check 2026-06-10

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