Research
Hormonal
In normogonadal men, lower plasma bioavailable testosterone levels are predictive of greater fat deposition in subcutaneous truncal and peripheral adipose tissues.
In men with normal testosterone, lower levels within the normal range are associated with higher subcutaneous fat, especially around the trunk. This suggests that maintaining healthy testosterone levels may help manage body fat distribution, although it is not the sole determinant of insulin resistance.
GoodSupportsHIGH confidence
We conclude that in normogonadal nondiabetic males, the variability in plasma bioavailable testosterone concentrations is predictive of the variability in fat deposition in the sc adipose tissue compartments of both truncal and peripheral areas.
Why this rating
Robust methodology with MRI and clamps, but correlation does not prove causation.
Source
Sex Steroid Hormones, Upper Body Obesity, and Insulin Resistance
Nicola Abate et al. · The Journal of Clinical Endocrinology & Metabolism · 2002
DOI 10.1210/jc.2002-020567
cross_sectional · n=57Cited 189×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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