Hormonal
Chronic exercise stimulates lipolysis in adipose tissue by normalizing the activity of lipolytic enzymes (ATGL and HSL), thereby facilitating the reduction of adipose tissue mass and preventing its accumulation.
To lose fat, you need to engage in regular physical activity. This activity triggers your body's fat-burning enzymes (like ATGL and HSL) to break down stored fat more efficiently. While you can't choose exactly where the fat comes from, consistent exercise helps your body manage fat stores better, especially if you have been overweight.
Thus, the results of most published studies suggest that physical exercise may stimulate lipolytic activity within AT, that may contribute to more efficient reduction of AT mass and/or prevent accumulation thereof.
Why this rating
The paper is a review summarizing multiple studies with mixed results (some show decreased phosphorylated HSL), indicating moderate consistency.
Source
Effect of Exercise on Fatty Acid Metabolism and Adipokine Secretion in Adipose Tissue
Adriana Mika et al. · Frontiers in Physiology · 2019
DOI 10.3389/fphys.2019.00026
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- Chronic exercise modulates adipokine secretion, generally reducing pro-inflammatory cytokines (like TNF-α and leptin) and improving insulin sensitivity, although the effects on specific adipokines like adiponectin and IL-6 can be variable or intensity-dependent.Moderate
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