Hormonal
Long-term testosterone therapy (1000 mg testosterone undecanoate every 12 weeks) in hypogonadal men significantly ameliorates metabolic syndrome components, including reducing total cholesterol, LDL, triglycerides, blood glucose, HbA1c, and blood pressure, while increasing HDL.
For hypogonadal men, long-term testosterone therapy (1000mg every 12 weeks) can significantly improve metabolic health markers like cholesterol, blood sugar, and blood pressure, potentially lowering heart disease risk. This should be considered under medical supervision for those with confirmed low testosterone and metabolic syndrome components.
Long-term T therapy, at physiological levels, ameliorates MetS components. These findings strongly suggest that T therapy in hypogonadal men may prove useful in reducing the risk of cardiometabolic diseases.
Why this rating
Observational registry study with no control group; potential confounding by lifestyle changes or concurrent medications not fully controlled.
Source
Long‐term testosterone therapy in hypogonadal men ameliorates elements of the metabolic syndrome: an observational, long‐term registry study
Abdulmaged M. Traish et al. · International Journal of Clinical Practice · 2013
DOI 10.1111/ijcp.12319
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