Research
Hormonal
Thyroid hormones (T4, T3) and insulin concentrations within the normal euthyroid range do not correlate with resting metabolic rate or protein turnover in healthy young adults.
If your thyroid levels are normal, they are not the primary driver of your metabolic rate differences. Focus on body composition rather than trying to 'optimize' normal hormone levels for metabolic boost.
GoodRefutesHIGH confidence
Neither resting metabolic rate nor protein turnover was related to total or free concentrations of thyroxine or triiodothyronine, within the euthyroid range.
Why this rating
Clear negative correlation reported with statistical analysis.
Source
Relationship of resting metabolic rate to body composition and protein turnover
Stephen Welle et al. · American Journal of Physiology-Endocrinology and Metabolism · 1990
DOI 10.1152/ajpendo.1990.258.6.e990
cross_sectional · n=47Cited 184×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Resting metabolic rate (RMR) is highly homogeneous in healthy young adults after adjusting for metabolically active tissue (total body potassium), with protein turnover explaining only a small but significant fraction (approx. 20%) of the remaining variability.Good
- Increased body fat is associated with elevated resting metabolic rate and protein turnover, even after accounting for lean body mass (total body potassium).Good
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