Hormonal
Anti-obesity medications (AOMs) are effective adjuncts for weight reduction and treating adiposopathy, but their efficacy is contingent upon adherence and individual metabolic response, with weight regain occurring if treatment is discontinued.
Use FDA-approved anti-obesity medications as a long-term tool to manage obesity, not just for short-term weight loss. They work best when combined with nutrition and exercise. Do not stop the medication just because you hit a target weight; stopping often leads to regain. Discuss specific drugs (like Semaglutide or Phentermine) with your doctor based on your health profile.
The purpose of anti-obesity medication treatment is to (a) serve as an adjunct to appropriate nutrition, physical activity, and healthful behavior to facilitate a more healthy body weight, (b) treat sick fat disease (adiposopathy) and its adverse cardiometabolic consequences... (d) slow the progression of weight regain...
Why this rating
The paper is a Clinical Practice Statement based on published citations and expert consensus, not a single primary RCT, but it synthesizes high-quality data.
Source
Anti-Obesity Medications and Investigational Agents: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2022
Harold Bays et al. · Obesity Pillars · 2022
DOI 10.1016/j.obpill.2022.100018
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