Adherence
Short sleep duration (<5 hours) and long sleep duration (>9 hours) are independently associated with a significantly increased risk of acute stroke, exhibiting a U-shaped relationship where short sleep shows a higher magnitude of association on univariate analysis but attenuates more than long sleep after adjusting for comorbidities.
Aim for 7 hours of sleep per night. Both sleeping less than 5 hours and more than 9 hours is associated with a significantly higher risk of stroke. If you consistently sleep outside this range, consider it a modifiable risk factor for cardiovascular health, especially if you have other risk factors like hypertension.
In our primary multivariable model, short nocturnal sleep duration (<5 hours: odds ratio [OR] 3.15, 95% CI 2.09–4.76) and long nocturnal sleep duration (>9 hours: OR 2.67, 95% CI 1.89–3.78) were associated with an increased odds of all stroke, compared with 7 hours (reference). A significant U-shaped association persisted in all multivariable models... This suggests that confounders and mediators of these associations differ and that long sleep duration is more likely to have an independent association with acute stroke.
Why this rating
Large international case-control study (INTERSTROKE) with 4,496 participants, adjusted for multiple confounders, though observational design limits causal inference.
Source
Sleep Patterns and the Risk of Acute Stroke
Christine E. Mc Carthy et al. · Neurology · 2023
DOI 10.1212/wnl.0000000000207249
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