Hormonal
Continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea syndrome (OSAS) significantly reduces in vitro platelet aggregability induced by epinephrine, restoring physiological diurnal patterns.
If you have obstructive sleep apnea, using your CPAP machine consistently every night for at least six months can significantly improve your blood's tendency to clot (platelet aggregability). This is a key mechanism for reducing your risk of heart attacks and strokes associated with sleep apnea. Ensure your device is delivering the prescribed pressure and that you are using it nightly to achieve these cardiovascular benefits.
Pretherapeutic platelet aggregability was significantly lowered by CPAP therapy both at 24:00 h (64.0±6.5 versus 55.3±6.7%, p<0.05) and at 06:00 h (64.1±6.5 versus 45.8±7.6%; p=0.01).
Why this rating
Small sample size (n=17), single-center study, and reliance on in vitro aggregometry rather than direct clinical cardiovascular outcomes.
Source
Platelet function in patients with obstructivesleep apnoea syndrome
Bernd Sanner et al. · European Respiratory Journal · 2000
DOI 10.1034/j.1399-3003.2000.16d14.x
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