Research
Hormonal
Higher serum HDL cholesterol is associated with higher bone mineral density at the femoral trochanter and a lower risk of vertebral fractures in postmenopausal women.
Maintaining healthy lipid profiles, including HDL, may support bone health in postmenopausal women, though the mechanism is not fully understood.
ModerateSupportsMEDIUM confidence
Serum high density lipoprotein cholesterol (HDLC) was positively related to femoral trochanter BMD (p = 0.0366) and was lower in the control group than the fracture group (p = 0.011).
Why this rating
Cross-sectional study, mechanism unclear.
Source
Relation between Obesity and Bone Mineral Density and Vertebral Fractures in Korean Postmenopausal Women
Kyongchol Kim et al. · Yonsei Medical Journal · 2010
DOI 10.3349/ymj.2010.51.6.857
cross_sectional · n=907Cited 179×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- In postmenopausal women, high percentage body fat and waist circumference are associated with lower bone mineral density and increased risk of vertebral fractures, whereas higher body weight is associated with higher bone mineral density.Good
- Higher serum glucose levels are positively correlated with bone mineral density in non-diabetic postmenopausal women, contradicting the assumption that hyperglycemia always reduces BMD.Moderate
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