Hormonal
Testosterone gel (Testim) at 100 mg/day normalizes serum testosterone levels in hypogonadal men, resulting in significant improvements in lean body mass, reduction in body fat percentage, and enhanced sexual function compared to a transdermal patch.
For men with clinically low testosterone, using a daily testosterone gel (like Testim) can effectively restore hormone levels. This leads to measurable gains in muscle mass, a slight reduction in body fat, and significant improvements in sexual desire and performance. It is generally well-tolerated with fewer skin issues than patches.
Testim produced dose-dependent improvements in all pharmacokinetic variables compared with Andropatch... The favourable pharmacokinetic profile and treatment outcome, combined with the enhanced tolerability of Testim, suggest that this new gel formulation is a safe and effective treatment in men with low serum testosterone levels and associated signs and symptoms of hypogonadism.
Why this rating
Randomized, multicentre, active-controlled clinical trial with 208 participants, though short duration (90 days).
Source
A novel testosterone gel formulation normalizes androgen levels in hypogonadal men, with improvements in body composition and sexual function
Tom McNicholas et al. · British Journal of Urology · 2003
DOI 10.1046/j.1464-410x.2003.04016.x
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