Hormonal
Oral administration of Lactobacillus plantarum strain Ln4 (5x10^8 CFU/day) attenuates diet-induced obesity, reduces epididymal fat mass, and improves insulin resistance in high-fat diet-fed mice.
This study suggests that consuming Lactobacillus plantarum strain Ln4 (500 million CFU daily) may help mitigate weight gain and improve insulin sensitivity in individuals consuming a high-fat diet. However, these results are from mice; human applicability is not yet established. Do not replace standard medical care with probiotics.
Oral administration of Ln4 reduced weight gain and epididymal fat mass in mice fed on a high-fat diet (HFD)... Ln4 administration induced a 40.6% reduction to the increased HOMA-IR index resulting from HFD feeding.
Why this rating
The study is an in vivo animal model (mice) with controlled conditions; results do not directly translate to human efficacy without clinical trials.
Source
Lactobacillus plantarum Strain Ln4 Attenuates Diet-Induced Obesity, Insulin Resistance, and Changes in Hepatic mRNA Levels Associated with Glucose and Lipid Metabolism
Eunjung Lee et al. · Nutrients · 2018
DOI 10.3390/nu10050643
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