Hormonal
Significant weight gain during early adulthood (ages 14 to 31) is a primary risk factor for the development of Polycystic Ovary Syndrome (PCOS) and its associated metabolic disturbances (dyslipidemia, hyperandrogenemia) by late adulthood.
If you are a woman in your teens or early 20s, maintaining a stable weight is crucial for preventing PCOS. The study shows that gaining significant weight during this specific window (ages 14-31) strongly predicts the development of PCOS and its metabolic risks later in life. Focus on weight management during these years rather than waiting until symptoms appear in your 30s or 40s.
Women with OA(cid:3)H at age 31 or diagnosis of PCOS by age 46 had the highest BMI at all ages compared with the controls. Increase of BMI between ages 14 and 31, but not between 31 and 46, was greater in women with isolated OA (P(cid:2).006), OA(cid:3)H (P(cid:2).001) and diagnosis of PCOS (P(cid:2).001) compared with controls.
Why this rating
Prospective population-based cohort study with long-term follow-up (32 years) and large sample size, though relying on self-reported symptoms for some groups.
Source
Weight Gain and Dyslipidemia in Early Adulthood Associate With Polycystic Ovary Syndrome: Prospective Cohort Study
Meri‐Maija Ollila et al. · The Journal of Clinical Endocrinology & Metabolism · 2015
DOI 10.1210/jc.2015-3543
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