Adherence
Structured behavioral interventions (diet, exercise, lifestyle counseling) are effective for modest weight loss and diabetes prevention in overweight/obese adults, whereas routine pharmacologic interventions (orlistat, metformin) are not recommended due to adverse event profiles outweighing benefits.
Focus on sustainable lifestyle changes (diet, exercise, counseling) rather than seeking quick fixes like weight-loss drugs. Behavioral interventions provide modest but clinically meaningful weight loss (approx. 3 kg) and diabetes prevention with fewer side effects than medications. Consult your primary care provider for a structured program.
For adults who are overweight or obese, we recommend that practitioners offer or refer to structured behavioural interventions aimed at weight loss. (Weak recommendation; moderate-quality evidence)... For adults who are overweight or obese, we recommend that practitioners not routinely offer pharmacologic interventions (orlistat or metformin) aimed at weight loss. (Weak recommendation; moderate-quality evidence)
Why this rating
Moderate-quality evidence for behavioral interventions; very low-quality evidence for prevention in normal-weight adults.
Source
Recommendations for prevention of weight gain and use of behavioural and pharmacologic interventions to manage overweight and obesity in adults in primary care
Paula Brauer et al. · Canadian Medical Association Journal · 2015
DOI 10.1503/cmaj.140887
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