Hormonal

Activation of brown adipose tissue (BAT) via cold exposure or pharmacological agents increases energy expenditure and reduces body fat mass in animal models, suggesting a viable anti-obesity therapeutic strategy.

Your body has a hidden calorie-burning system called brown fat, which is more active in lean, younger people. You can activate it by exposing yourself to cold temperatures (like cool showers or wearing lighter clothing in winter), which triggers your nervous system to burn fat for heat. While this works well in mice, human results vary, and older or obese individuals may have less active brown fat. Pharmacological drugs targeting this system are in development but not yet available.