Adherence
Higher total daily sedentary time is independently associated with increased cancer mortality risk in middle-aged and older adults, regardless of moderate-to-vigorous physical activity (MVPA) levels.
If you are over 45, your total daily sitting time matters for your long-term survival risk, independent of how much you exercise. Use an accelerometer or pedometer to track total sedentary minutes. Aim to reduce total sitting time, not just to 'get your workout in,' but to lower your baseline risk profile.
In multivariable-adjusted models, including MVPA, greater total sedentary time was associated with a greater risk of cancer mortality (tertile 2 vs tertile 1: hazard ratio [HR], 1.45; 95% CI, 1.00-2.11; tertile 3 vs tertile 1: HR, 1.52; 95% CI, 1.01-2.27).
Why this rating
Prospective cohort study with objective accelerometer measurement and large sample size (n=8002), though observational design limits causal inference.
Source
Association of Sedentary Behavior With Cancer Mortality in Middle-aged and Older US Adults
Susan C. Gilchrist et al. · JAMA Oncology · 2020
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