Research
Hormonal
Reduction in melatonin amplitude caused by circadian misalignment correlates with reductions in the amplitude of core body temperature, cortisol, and alertness rhythms.
If your melatonin rhythm is dampened (e.g., due to shift work or jet lag), your other bodily rhythms like body temperature and alertness are likely also dampened. Restoring circadian alignment may help restore the amplitude of these rhythms.
ModerateQualifiesMEDIUM confidence
Individual differences in amplitude reduction of the melatonin rhythm correlated with the amplitude of body temperature, cortisol and alertness.
Why this rating
Correlational finding within a robust study design.
Source
Amplitude Reduction and Phase Shifts of Melatonin, Cortisol and Other Circadian Rhythms after a Gradual Advance of Sleep and Light Exposure in Humans
Derk‐Jan Dijk et al. · PLoS ONE · 2012
DOI 10.1371/journal.pone.0030037
rct · n=14Cited 170×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Gradual advancement of the sleep-wake schedule combined with moderate indoor light exposure (90-150 lux) fails to advance the circadian phase and significantly reduces the amplitude of the melatonin rhythm.Good
- Bright light exposure (>10,000 lux) timed to follow the core body temperature minimum successfully advances the circadian phase of melatonin and cortisol by approximately 8-10 hours.Good
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