Hormonal
Liraglutide 3.0 mg/day significantly reduces body weight in adults with obesity or overweight (BMI ≥30 or ≥27 with comorbidities) compared to placebo, with effects sustained over 56 weeks.
If you have obesity or are overweight with related health issues like high blood pressure, a daily 3.0 mg injection of liraglutide, combined with a modest calorie deficit and exercise, can help you lose significantly more weight than lifestyle changes alone. Start with a lower dose to let your body adjust to potential stomach side effects, then increase to the full dose over several weeks.
At week 56, liraglutide-treated subjects achieved a weight loss of 8.4 ± 7.3 kg vs. placebo group with a loss of 2.8 ± 6.5 kg (ETD –5.6 kg, p ≤ 0.001).
Why this rating
Based on large-scale, double-blinded, randomized controlled trials (SCALE Obesity and Prediabetes, N=3731).
Source
A 2021 Update on the Use of Liraglutide in the Modern Treatment of ‘Diabesity’: A Narrative Review
Mariana Cornelia Tilinca et al. · Medicina · 2021
DOI 10.3390/medicina57070669
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- Liraglutide 1.8 mg/day improves glycemic control (HbA1c reduction) in patients with Type 2 Diabetes compared to placebo, rosiglitazone, glimepiride, insulin glargine, and exenatide.Good
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