Research

Hormonal

Once-weekly subcutaneous semaglutide (2.4 mg) combined with lifestyle intervention significantly reduces body weight in adults with obesity or overweight.

If you have obesity or overweight with related health issues, ask your doctor about once-weekly semaglutide injections (2.4 mg). It works by suppressing appetite and slowing digestion, leading to significant weight loss (around 15% in trials) when combined with diet and exercise. Be aware of potential stomach issues like nausea, which often improve over time.

StrongSupportsVERY_HIGH confidence
Among obese adults, subcutaneous Semaglutide (2.4 mg) given once weekly promotes weight loss via appetite and hunger suppression, decreases energy intake, controls eating, and depresses the relative fondness for fatty, energy-dense foods.
Nasser M. Alorfi et al. · Clinical Pharmacology Advances and Applications · 2022

Why this rating

Based on multiple Phase III randomized, double-blind, placebo-controlled clinical trials.

Source

Clinical Impact of Semaglutide, a Glucagon-Like Peptide-1 Receptor Agonist, on Obesity Management: A Review

Nasser M. Alorfi et al. · Clinical Pharmacology Advances and Applications · 2022

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