Macro partitioning
High carbohydrate intake (defined as the highest category in prospective cohorts) is associated with a significantly increased risk of cardiovascular disease (CVD), with a pooled hazard ratio of 1.15 compared to the lowest intake.
If you consume a high-carbohydrate diet, particularly if carbohydrates make up more than 60% of your total daily calories, consider reducing this proportion. This meta-analysis suggests that lowering high carbohydrate intake is associated with a lower risk of cardiovascular disease. Focus on balancing macronutrients rather than eliminating carbs entirely.
The meta-analysis found that individuals with the highest carbohydrate intake had a 1.15-fold increased risk of CVD compared to those with the lowest intake (hazard ratio, HR: 1.15, 95% confidence interval, CI: 1.07–1.23).
Why this rating
Systematic review and meta-analysis of 23 prospective cohort studies provides high-level observational evidence, though residual confounding is acknowledged.
Source
Carbohydrate Intake and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Prospective Studies
Unhui Jo et al. · Nutrients · 2023
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