Hormonal
Older adults require higher total protein intakes (1.0–1.5 g/kg/d) and higher EAA/leucine density to overcome anabolic resistance and maximize muscle protein synthesis.
If you are over 65, aim for 1.0 to 1.5 grams of protein per kilogram of body weight daily. Focus on protein sources rich in essential amino acids, especially leucine, to help your muscles respond better to food and exercise. This helps prevent age-related muscle loss.
Expert groups recommend intakes of 1.0–1.5 g/kg/d for older adults (≥65 y) to minimize age-related declines in health and function.
Why this rating
The paper cites expert group recommendations and multiple studies on MPS in older adults, providing robust evidence for this specific demographic.
Source
Understanding Dietary Protein Quality: Digestible Indispensable Amino Acid Scores and Beyond
Joseph J. Matthews et al. · Journal of Nutrition · 2025
DOI 10.1016/j.tjnut.2025.07.005
More from this paper
- Processing and cooking methods that reduce antinutrients, denature proteins, and reduce food particle size improve dietary protein quality by increasing essential amino acid (EAA) digestibility and bioavailability.Good
- High-temperature cooking and prolonged storage can decrease protein quality by reducing the bioavailability of essential amino acids, particularly lysine, through the Maillard reaction and protein aggregation.Good
Related findings · Hormonal
- Initial treatment for type 2 diabetes should be a combination of metformin and either an SGLT-2 inhibitor or a GLP-1 receptor agonist to achieve cardiorenal protection, rather than monotherapy or older agents like sulfonylureas.Strong
- For patients with specific monogenic obesity syndromes (leptin deficiency, POMC/PCSK1/LEPR mutations), targeted pharmacotherapy (recombinant leptin or setmelanotide) is highly effective and should be prioritized, unlike in polygenic obesity.Strong
- Continued weekly administration of 2.4 mg subcutaneous semaglutide prevents weight regain and promotes further weight loss in adults with overweight or obesity, whereas switching to placebo results in significant weight regain.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →