Research
Adherence
Physical activity can significantly reduce the genetic risk of obesity, specifically by mitigating the effects of the FTO gene.
If you have a family history of obesity, regular physical activity is your most powerful tool to counteract your genetic risk. Aim for consistent activity to reduce your FTO gene's impact by nearly 30%.
GoodQualifiesHIGH confidence
the impact of FTO, a well-known obesity gene, was reduced by nearly 30% in physically active individuals compared to inactive individuals.
Why this rating
Based on a meta-analysis of over 200,000 individuals.
Source
Identifying obesity subtypes: A review of studies utilising clinical biomarkers and genetic data
Angela Abraham et al. · Diabetic Medicine · 2023
DOI 10.1111/dme.15226
narrative_reviewCited 20×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →