Research

Adherence

An intensive lifestyle intervention (ILI) involving caloric restriction and physical activity improves preference-based health-related quality of life (HRQOL) in individuals with type 2 diabetes, but this improvement is statistically significant and clinically relevant primarily in the short term (first year), with long-term effects being small, inconsistent across measurement instruments, and often failing to reach minimally important difference (MID) thresholds.

If you have type 2 diabetes, an intensive lifestyle program focusing on diet and exercise will likely improve how you feel about your health, especially in the first year. However, expect the benefits to plateau and become smaller over time. To maintain any quality of life gains, you must actively work to prevent weight regain, as the study shows that compliance drops and weight is regained after the first year, eroding these benefits.

GoodQualifiesHIGH confidence
ILI aimed at reducing body weight among persons with overweight or obesity and type 2 diabetes improves preference-based HRQOL in the short term, but its long-term effect is unclear.
Ping Zhang et al. · Obesity · 2016

Why this rating

Large multisite randomized controlled trial (n=5,145) with long follow-up (9 years), though the effect size is small and mixed across instruments.

Source

Impact of intensive lifestyle intervention on preference‐based quality of life in type 2 diabetes: Results from the<scp>L</scp>ook<scp>AHEAD</scp>trial

Ping Zhang et al. · Obesity · 2016

rct · n=5145Cited 19×
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