Hormonal
Acute moderate altitude hypoxia (2320m) does not enhance the hormonal (GH, Cortisol, Testosterone) or inflammatory (IL-6, IL-10, TNF-alpha) response to a single hypertrophy-oriented resistance training session compared to normoxia.
If you are training at moderate altitude (approx 2300m), do not expect a single resistance training session to trigger a superior acute hormonal or inflammatory response compared to training at sea level. The anabolic signaling environment (GH, Testosterone) remains similar to normoxia. Focus on maintaining training volume and intensity rather than relying on altitude for acute hormonal amplification.
The results suggest that a RT session at H does not differentially affect the hormonal, inflammatory, and miR-378 responses compared to N.
Why this rating
Randomized counterbalanced design with trained subjects, though small sample size (n=13) and assay sensitivity limitations reduce certainty.
Source
Hormonal and Inflammatory Responses to Hypertrophy-Oriented Resistance Training at Acute Moderate Altitude
Cristina Benavente et al. · International Journal of Environmental Research and Public Health · 2021
DOI 10.3390/ijerph18084233
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