Hormonal
Short-term testosterone replacement therapy (200mg intramuscular testosterone cypionate every 3 weeks for 6 months) significantly improves libido and reduces waist circumference in males with late-onset hypogonadism.
If you are a man over 50 with clinically diagnosed low testosterone, short-term testosterone replacement therapy (200mg every 3 weeks) can significantly improve your sex drive and reduce belly fat within 6 months. This study also found no dangerous spikes in prostate markers or blood thickness during this period, suggesting it can be safe with proper monitoring.
Six months of testosterone replacement improved sexuality and body composition, with prostatic and hematological safety.
Why this rating
Small sample size (n=62), short duration (6 months), and use of oral vitamins as a control rather than a placebo injection limit generalizability.
Source
Short term testosterone replacement therapy improves libido and body composition
Edésio Seara de Andrade Júnior et al. · Arquivos Brasileiros de Endocrinologia & Metabologia · 2009
DOI 10.1590/s0004-27302009000800014
Related findings · Hormonal
- Initial treatment for type 2 diabetes should be a combination of metformin and either an SGLT-2 inhibitor or a GLP-1 receptor agonist to achieve cardiorenal protection, rather than monotherapy or older agents like sulfonylureas.Strong
- For patients with specific monogenic obesity syndromes (leptin deficiency, POMC/PCSK1/LEPR mutations), targeted pharmacotherapy (recombinant leptin or setmelanotide) is highly effective and should be prioritized, unlike in polygenic obesity.Strong
- Continued weekly administration of 2.4 mg subcutaneous semaglutide prevents weight regain and promotes further weight loss in adults with overweight or obesity, whereas switching to placebo results in significant weight regain.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →