Hormonal
Once-weekly subcutaneous semaglutide 2.4 mg significantly improves weight-related quality of life (WRQOL) and health-related quality of life (HRQOL) in East Asian adults with overweight or obesity, specifically enhancing physical functioning, psychosocial well-being, and total quality of life scores compared to placebo.
If you are an East Asian adult with overweight or obesity, once-weekly semaglutide 2.4 mg, combined with a modest 500-kcal daily calorie deficit and 150 minutes of weekly physical activity, has been shown to significantly improve your physical functioning, psychosocial well-being, and overall quality of life compared to placebo. This treatment helps you feel better in social situations and perform daily activities more comfortably.
Treatment with semaglutide 2.4 mg improved aspects of WRQOL and HRQOL in people from East Asia with overweight/obesity.
Why this rating
Randomized controlled trial with a clear treatment arm, though the sample size (n=401) is moderate and multiplicity was not controlled for.
Source
Effect of once‐weekly subcutaneous semaglutide 2.4 mg on weight‐ and health‐related quality of life in an East Asian population: Patient‐reported outcomes from the <scp>STEP</scp> 6 trial
Ronette L. Kolotkin et al. · Clinical Obesity · 2023
DOI 10.1111/cob.12589
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