Research
Hormonal
Semaglutide promotes significant weight loss in individuals with obesity, both with and without type 2 diabetes.
If you have obesity, ask your doctor about semaglutide. It is a once-weekly injection that has been proven to produce significant weight loss, often exceeding 15% of body weight, when combined with lifestyle changes.
StrongSupportsHIGH confidence
In STEP trials 1, 3, 4, and 8, participants without T2D achieved mean weight losses ranging from 14.9% to 17.4% from baseline to week 68 [8,58–60].
Why this rating
Based on multiple large RCTs (STEP program) with statistically significant results.
Source
Semaglutide: a key medication for managing cardiovascular-kidney-metabolic syndrome
Richard J. MacIsaac · Future Cardiology · 2025
narrative_reviewCited 11×
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