Research
Hormonal
GLP-1 receptor agonists (GLP-1RAs) induce significant weight loss, leading to improved physical functioning, daily living capacity, and mental well-being, despite common gastrointestinal side effects.
GLP-1RAs are effective for weight loss and improving daily functioning. Expect gastrointestinal side effects like nausea, which often subside after a few weeks. The benefits of weight loss and improved mobility often motivate patients to persist despite these side effects.
GoodSupportsHIGH confidence
Patients experience improved physical functioning, well-being and active daily living as a result of weight loss
Why this rating
Based on a systematic review of 9 studies including RCTs and qualitative interviews.
Source
Patients’ experiences with GLP1-RAs – a systematic review
Christoffer Kraul Ibsen et al. · Scandinavian Journal of Primary Health Care · 2025
DOI 10.1080/02813432.2025.2477141
systematic_reviewCited 9×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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