Hormonal
Short-term time-restricted feeding (8h window) alters the rhythmicity of serum lipids and muscle amino acids without perturbing core clock gene expression in skeletal muscle.
If you practice time-restricted feeding, expect changes in how your body processes fats and amino acids throughout the day, specifically by increasing the 'peaks' of certain metabolic signals in muscle. This happens even if your body's core biological clock genes remain unchanged. Focus on the timing of nutrient availability rather than trying to 'reset' your biology.
In conclusion, short-term TRF in overweight men affects the rhythmicity of serum and muscle metabolites and regulates the rhythmicity of genes controlling amino acid transport, without perturbing core clock gene expression.
Why this rating
Randomized crossover design with 11 participants, rigorous metabolomic profiling, but small sample size.
Source
Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression
L Lundell et al. · Nature Communications · 2020
DOI 10.1038/s41467-020-18412-w
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